Empagliflozin 12.5 mg + Metformin 500 mg tablet ( other generic )

Empagliflozin and metformin is a combination medication used to treat *type 2 diabetes mellitus*. This oral anti-diabetic medication works by: Primary Mechanisms 1. *Empagliflozin*: Blocks the reabsorption of glucose in the kidneys, increasing glucose excretion in the urine. 2. *Metformin*: Decreases glucose production in the liver, increases insulin sensitivity, and enhances glucose uptake by muscles. Therapeutic Uses 1. *Improves glycemic control*: Reduces hemoglobin A1c (HbA1c) levels, fasting plasma glucose, and postprandial glucose. 2. *Weight management*: Can lead to weight loss due to increased glucose excretion and reduced insulin levels. 3. *Cardiovascular benefits*: Empagliflozin has been shown to reduce the risk of cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke. Additional Benefits 1. *Reduced blood pressure*: Empagliflozin can help lower blood pressure in patients with type 2 diabetes. 2. *Kidney protection*: May slow the progression of kidney disease in patients with type 2 diabetes. Important Considerations 1. *Contraindications*: Not recommended for patients with severe kidney impairment, end-stage renal disease, or those on dialysis. 2. *Side effects*: Common side effects include increased urination, thirst, genital yeast infections, and hypoglycemia.